For years, scientists and doctors have treated vaccine skepticism as a knowledge problem. If patients were hesitant to get vaccinated, the thinking went, they simply needed more information.

But as public health officials now work to convince Americans to get Covid-19 vaccines as quickly as possible, new social science research suggests that a set of deeply held beliefs is at the heart of many people’s resistance, complicating efforts to bring the coronavirus pandemic under control.

A portion of those who are hesitant will eventually get vaccinated. According to Drew Linzer, the director of the polling firm Civiqs, fewer people are unsure about the vaccines now than in the fall, but the percentage of hard noes has remained fairly constant. As of last week, about 7 percent say they are unsure, he said, and about 24 percent say they will never take it.

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